Search on: GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR 
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Descriptor English:   Glial Cell Line-Derived Neurotrophic Factor 
Descriptor Spanish:   Factor Neurotrófico Derivado de la Línea Celular Glial 
Descriptor Portuguese:   Fator Neurotrófico Derivado de Linhagem de Célula Glial 
Synonyms English:   GDNF
GDNF Growth Factor
Glial Cell-Line Derived Neurotrophic Factor
Glial Cell Line Derived Neurotrophic Factor
Growth Factor, GDNF  
Tree Number:   D12.644.276.860.381.500
D12.776.467.860.381.500
D12.776.631.600.381.500
D23.529.850.381.500
Definition English:   The founding member of the glial cell line-derived neurotrophic factor family. It was originally characterized as a NERVE GROWTH FACTOR promoting the survival of MIDBRAIN dopaminergic NEURONS, and it has been studied as a potential treatment for PARKINSON DISEASE. 
Indexing Annotation English:   GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTORS is also available
History Note English:   2006(1993) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   51102 
Unique Identifier:   D051100 

Occurrence in VHL:
 

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